Ipso-Lux © · Open fluidic head
SPR and microscopy,
in the same experiment
Position a microscope objective directly above the gold surface and combine binding kinetics with fluorescence, brightfield, or photoactivation, in real time.
Open fluidic head
A unique open access
to your SPR cell
- An open fluidic head allows approaching a microscope objective directly to the SPR cell.
- Visualize what's happening inside the 100 µm transparent microfluidic channel, in parallel with the live SPR sensorgram.
- Observe the reaction through a 1 mm glass ceiling in the 2 independent fluidic channels.
Open-aperture fluidic head — 2 independent channels
Ipso-Lux = Ipso-LAB + open fluidic head
A glass-top flow cell opens optical access above the SPR chip — illuminate, excite, or image your sample while SPR kinetics run continuously at the gold surface.
Ipso-LAB full specificationsResearch applications
Ipso-Lux opens SPR
to light-driven science
Photoswitchable binding kinetics
Illuminate the sample during the SPR run and watch kon and koff respond as your molecule toggles between isomers — azobenzenes, diarylethenes, or any photoswitch. Both binding states captured in a single run, under controlled illumination.
Optogenetic protein interactions
Activate a LOV domain, cryptochrome, or phytochrome on the sensor chip with a light pulse and immediately record the change in binding kinetics. One measurement bridges structural biophysics and light-driven cellular function.
Fluorescence & TIRF imaging
Place a microscope objective above the chip and capture TIRF or brightfield images while the SPR sensorgram runs. Spatially resolved molecular events and ensemble binding kinetics — simultaneous, on the same sample.
An experiment in mind
with Ipso-Lux?
Share your measurement challenge and our scientists will assess how Ipso-Lux fits your workflow.